Founder of the Colbé Trust, a fudiciary charity for medical consumers and participants in clinical trials.
Early in my career at GSK, I spent two years working to keep an antibiotic, called co-trimoxazole (Septrin), from being withdrawn from the market. In international companies, when 200-300 people work on a single product, I was the only one assigned to it. I responded to every lengthy medical and regulatory enquiry from medicines agencies, … More Co-trimoxazole
Healing rewires the brain — resilience is the upgrade. 🧠 1. The Survival Brain Takes Over The brain goes into “fight, flight, or freeze” mode when facing a stressful experience such as trauma. This is controlled by the amygdala, the brain’s alarm system. It becomes overactive, always scanning for risk, even when the person is safe. 🧠 … More Neuroplastic change
In 1948, in the shadow of a war that had affected Britain, a new hope was born. Clement Attlee’s government, driven by a vision of fairness and compassion, laid the foundations of the National Health Service—a system built on the principle that healthcare should be a right, not a privilege. It was a profound moral … More NHS❤️
Each of our cells contains hundreds of small bean-shaped mitochondria — subcellular structures, or organelles, that provide the energy needed for normal functioning. Mitochondria have their own circular genome with 37 genes. We inherit this mitochondrial DNA, so the makeup of the DNA’s code stays relatively consistent from one generation to the next. New research suggests that … More The Powerhouse of Mitochondria
Contingent or secondary gaslighting is a form of manipulation that occurs when individuals or groups, usually those who are close to the individual, or in positions of authority, reinforce and even perpetuate the behaviour as initiated by the primary instigator. As a result, this will further undermine that person’s sense of reality, and exacerbate their … More Focus on psychology
For decades the neuroscience community has focused almost exclusively on beta-amyloid in the brain as the primary cause of Alzheimer’s disease [AD]. Billions have been spent developing dozens of drugs designed to rid the brain of beta-amyloid plaques. However, new research from Sweden suggests that local or systemic infection may be contributing to Alzheimer’s disease. … More Could infection contribute to Alzheimer’s?
Dopamine, a neurotransmitter associated with reward and pleasure, plays a crucial role in Attention Deficit Hyperactivity Disorder (ADHD). This condition is characterized by persistent patterns of inattention, hyperactivity, and impulsivity. Dopamine is involved in the regulation of attention, motivation, and executive functions, making it a key player in understanding ADHD. Individuals diagnosed with ADHD often … More The role of dopamine in ADHD
Alzheimer’s disease is a neurodegenerative disorder that affects millions of patients worldwide. While there is no cure, significant advances have been made in our understanding of the condition and the development of potential treatments. This article will explore some of the key advances in Alzheimer’s disease research and treatment. One of the most significant breakthroughs … More Advances in Treatment of Alzheimer’s Disease
This is a review of the regulatory evidence regarding a product by the name of pregabalin by our patient advocacy charity, Colbé Trust. Public records demonstrate that the drug has been identified as the cause of fatality of the actor and comedian, Robin Williams: Relevant Background The gamma‐aminobuyric acid (GABA) analogues, including gabapentin and pregabalin … More The Blinding Analgesic
What is the first sign of a covert narcissist? Amongst the dark triad personality disorders, covert (closet) narcissists are the hardest to spot. Although they have the symptoms of Narcissistic Personality Disorder (NPD), they embody them in a subtle way. They exhibit no immediate sign of grandiosity, self-exaltation, or self-deification. The delusional arrogance, or ability … More Covert Narcissism
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